Arrhythmias in Patients with Cardiac Amyloidosis: A Comprehensive Review on Clinical Management and Devices

Cardiac amyloidosis (CA) is a rare but potentially life-threatening disease in which misfolded proteins accumulate the cardiac wall tissue. Heart rhythm disorders CA, including supraventricular arrhythmias, conduction system disturbances, or ventricular play major role CA morbidity and mortality, thus require supplementary management. Among them, AF most frequent arrhythmia during hospitalizations associated with significantly higher while arrhythmias are also common usually poor prognosis. Early diagnosis of potential arrythmias could be performed through ECG, Holter monitoring, and/or electrophysiology study. Clinical management these patients quite significant, it includes initiation amiodarone digoxin AF, electrical cardioversion, ablation specific indication, as well anticoagulants all patients, independent CHADS-VASc score, for intracardiac thrombus. Moreover, identification that benefit from prophylactic pacemaker implantation CRT ICD both increase survival rates improve their quality life.